America's Next Top Model prides itself on shaking up the fashion world.
In the past the show has featured twins, plus sizes and girls with disabilities.
But as it returns for its 11th season it is set to push the boundaries of conventional beauty once again by featuring the first ever transsexual contestant.
Hopeful: Transsexual Isis is one of 14 aspiring models vying to win a lucrative contract
The reality show headed by ex-model Tyra Banks features 14 girls competing to win a lucrative modelling contract.
This year the hopefuls will include 22-year-old transgender Isis among its contestants.
The transsexual beauty was discovered on the last series of the show in when she appeared in a homeless photo shoot.
Familiar face: Isis was discovered when she appeared in a homeless shoot in season 10 of the show
The former non-profit worker from Prince George’s County, Maryland, identified herself as 'a woman born physically male,' in an interview with US Weekly.
She said: 'My cards were dealt differently.'
Asked if she wanted to be a role model for others, she replied: 'I like to help people, but I’m here to follow my dreams.'